While sleeping on the roof, Scooby and Shaggy are abducted. Lester then offers to let the gang stay for the night. The gang goes to his house to see them, but they turn out to be nothing more than paintings by Lester. A man named Lester claims to have been abducted once before and claims that he has pictures. The chef, Sergio, says that cattle have also vanished overnight without a trace and people left town as a result. The diner waitress, Dottie, says that they have never seen aliens, but do see strange lights and hear strange sounds at night.

Shaggy and Scooby run into the diner in panic, claiming to have seen aliens. Two aliens then approach them from behind and chase them towards the town. When they chase it into the mouth of a cave, they see a glow in the distance. While waiting, Shaggy and Scooby fight over a Scooby Snack before encountering a fictional animal called a jackalope. While Scooby-Doo and Shaggy stay with the van, the rest of the gang walk to the town, where they ask for help at a diner. The gang find themselves on the outskirts of a small town. A sand storm kicks in and Shaggy accidentally makes a turn onto government property, and a subsequent sighting of a UFO causes him to lose control and crash into a cactus. The Mystery Machine is driving through a desert. When it disappears, Steve gets something on the radar. At the SALF station, Max, Laura and Steve suddenly get a loud reading that is off the charts.

Scooby doo and the alien invaders